Recorded on 03/31/2026

Beyond the Basics: Health, Performance, & the Science of Longevity

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Recorded on March 31, 2026.

In this conversation, Dr. Liz Gilman of Mayo Clinic offered a clear and pragmatic framework for thinking about health not as an afterthought, but as a core driver of long-term performance. Grounded in data from CEO populations and her work with executive patients, she reframed longevity as a function of disciplined fundamentals, thoughtful use of emerging diagnostics, and a willingness to manage risk proactively—much like any other form of capital.

Key Themes

The hidden risks of high performance
Success often carries unseen health tradeoffs. Elevated stress, inconsistent sleep, prolonged sitting, and frequent travel create measurable increases in long-term risk, including higher all-cause mortality and cardiovascular strain. While quality of life remains high among executives, these underlying patterns can quietly erode health over time.

Health as a discipline, not a luxury
Dr. Gilman challenged the notion that self-care is optional or secondary. Just as families steward financial capital across generations, health requires the same intentionality. Prioritizing physical and cognitive capacity is foundational to sustaining leadership, decision-making, and longevity.

The non-negotiables: highest return on investment
At the core are a small number of evidence-based habits that deliver outsized impact:

  • Sleep as a force multiplier, with a target of seven or more hours per night
  • Strength training and movement, supporting metabolic health, balance, and longevity
  • Consistent aerobic activity, with 150 minutes per week as a baseline
  • Nutrition fundamentals, including adequate protein and a whole-food, plant-forward approach
  • Stress management, even in small daily increments

Early detection: promise with complexity
Emerging tools like multi-cancer detection blood tests and whole-body MRI offer the potential to identify disease earlier, particularly for cancers without standard screening. At the same time, they introduce ambiguity:

  • False positives and incidental findings can lead to additional testing and anxiety
  • Not all detected conditions are actionable
  • These tools remain adjuncts, not replacements, for guideline-based screening

Data is expanding, but judgment still matters
From wearables to AI-integrated health platforms, the volume of personal health data continues to grow. While these tools may enhance early detection and awareness, their value depends on how individuals engage with the insights. Data alone does not change outcomes—behavior does.

Emerging science: biologic age and beyond
Advancements in epigenetics and AI are beginning to estimate “biologic age” and cellular health. While promising, these tools currently serve more as directional indicators than prescriptive guides. The underlying message remains consistent: lifestyle choices meaningfully influence long-term health trajectories.

Back to basics, with intention
Despite rapid innovation, the most reliable path forward remains grounded in fundamentals. Dr. Gilman encouraged participants to revisit the essentials over the next 30 days:

  • Prioritize sleep and recovery
  • Build strength and move consistently throughout the day
  • Close gaps in preventive screenings
  • Create space for daily stress downshifting

About Dr. Liz A. Gilman

Liz Gilman, MD, MSM, is an Associate Professor of Medicine at Mayo Clinic and Vice Chair of Outpatient Practice Transformation in Mayo Clinic’s Department of Medicine. She serves as Practice Leader for Mayo Clinic’s Executive Health Program and new Mayo Clinic 365 offering, partnering with CEO and business leader patients to prioritize prevention, performance, and long-term health.

Her work focuses on proactive risk assessment, early cancer detection, and helping individuals make informed decisions about screening, diagnostics, and lifestyle strategy. She works at the intersection of medical evidence and practical implementation - translating complex data into clear, actionable guidance.

Board-certified in Internal Medicine and Anatomic and Clinical Pathology, she holds a Master of Science in Management / Digital Transformation of Healthcare. In addition to clinical practice, she leads system-level initiatives designed to improve patient access, simplify care delivery, and support sustainable performance in demanding professional environments.

*Third-party prepared biographies are provided for informational purposes only; Cresset does not validate their accuracy or completeness.

Featuring

Dr. Liz A. Gilman

Dr. Liz A. Gilman

Internist, Pathologist at Mayo Clinic

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